Recent Publications

Jensen, D.E.A., Ebmeier, K.P., Suri, S. et al. Nuclei-specific hypothalamus networks predict a dimensional marker of stress in humans. Nat Commun 15, 2426 (2024). https://doi.org/10.1038/s41467-024-46275-y

Klein-Flügge MC, Fouragnan EF, Martin E. The importance of acoustic output measurement and monitoring for the replicability of transcranial ultrasonic stimulation studies. Brain Stimul. 2023 Dec 12;17(1):32-34. doi: 10.1016/j.brs.2023.12.002.

Pauli R, Brazil IA, Kohls G, Klein-Flügge MC, Rogers JC, Dikeos D, Dochnal R … Lockwood P. Action Initiation and Punishment Learning Differ from Childhood to Adolescence While Reward Learning Remains Stable. Nature Communications 14, no. 1 (14 September 2023): 5689. https://doi.org/10.1038/s41467-023-41124-w.

Attali D, Tiennot T, Schafer M, Fouragnan E, Sallet J, Caskey CF, Chen R, Darmani G, Bubrick EJ, Butler C, Stagg C, Klein-Flügge MC, Verhagen L, Yoo S, Butts Pauly K, Aubry JF. Three-Layer Model with Absorption for Conservative Estimation of the Maximum Acoustic Transmission Coefficient through the Human Skull for Transcranial Ultrasound Stimulation. Brain Stimulation 16, no. 1 (2023): 48–55.

Klein-Flügge MC, Jensen DEA, Takagi Y, Priestley L, Verhagen L, Smith S, Rushworth, MFS, Relationship between Nuclei-Specific Amygdala Connectivity and Mental Health Dimensions in Humans, Nat Hum Beh, 2022, https://doi.org/10.1038/s41562-022-01434-3.

Klein-Flügge MC, Bongioanni A, and Rushworth MFS. Medial and Orbital Frontal Cortex in Decision-Making and Flexible Behavior’. Neuron 0, no. 0 (14 June 2022). https://doi.org/10.1016/j.neuron.2022.05.022.

Sel AS, Verhagen L, Angerer K, David R, Klein-Flügge MC, and Rushworth MFS. Increasing and Decreasing Interregional Brain Coupling Increases and Decreases Oscillatory Activity in the Human Brain’. PNAS 118, no. 37 (2021)

Takagi Y, Hunt L, Woolrich MW, Behrens TEJ†, Klein-Flügge MC† (2021) Adapting non-invasive human recordings along multiple task-axes shows unfolding of spontaneous and over-trained choice [†joint senior authors] ELife 10 (11 May 2021): e60988.

Bongioanni A, Folloni D, Verhagen L, Sallet J, Klein-Flügge MC†, Rushworth MFS† (2021) Activation and disruption of a neural mechanism for novel choice in monkeys, Nature, 6 January 2021, 1–5, https://doi.org/10.1038/s41586-020-03115-5 [†joint senior authors]

Harrison, OK, Guell X†, Klein-Flügge MC†, Barry RL† (2021) Structural and functional connectivity beyond the cortex, Neuroimage 240: 118379 (invited review) († equal contribution)

Wittmann, MK, Trudel N, Trier H, Klein-Flügge MC, Sel A, Verhagen L, and Rushworth MFS (2021) Causal Manipulation of Self-Other-Mergence in Dorsomedial Prefrontal Cortex, Neuron 109, no.14: 2353-2361.e11

Müller T, Klein-Flügge MC, Manohar S, Husain M, Apps MAJ (2021) Neural and computational mechanisms of momentary fatigue and persistence in effort-based choice, Nature Communications 12, no.1:4593

Jensen DEA, Leoni V, Klein-Flügge MC, Ebmeier KP, Suri S (2021), The effect of diet markers on the ageing brain: A systematic review, Ageing Research Reviews 70 (1 September 2021): 101360

Lockwood PL*, Klein-Flügge MC*, Abdurahman A, Crockett MJ (2020) Model-Free Decision Making Is Prioritized When Learning to Avoid Harming Others, PNAS 117, no 44:27719–30 https://doi.org/10.1073/pnas.2010890117 [*shared first authors]

Wittmann MK, Fouragnan E, Folloni D, Klein-Flügge MC, Chau B, Khamassi M, Rushworth, MFS (2020) Global reward state affects learning, the raphe nucleus, and anterior insula in monkeys, Nature Communications 11, 3771

Trudel N, Scholl J, Klein-Flügge MC, Fouragnan E, Tankelevitch L, Wittmann MK, Rushworth MFS (2020) Polarity of subjective uncertainty in ventromedial prefrontal cortex changes with behavioural adaptation Nat Hum Beh

Chau BKH, Law C, Lopez-Persem A, Kolling N, Klein-Flügge MC, Rushworth MFS (2020) Consistent replication of multiple distractor effects in multiple data sets, eLife, 9: e53850

Lockwood PL, Klein-Flügge MC (2020) Computational modelling of social cognition and behaviour – a reinforcement learning primer Social Cognitive and Affective Neuroscience, https://doi.org/10.1093/scan/nsaa040

Klein-Flügge MC, Wittmann, MK, Shpektor A, Jensen DEA, Rushworth MFS (2019) Multiple associative structures created by reinforcement and incidental statistical learning mechanisms, Nature Communications, 10,1:1–15.

Fouragnan EF, Chau BKH, Folloni D, Kolling N, Verhagen L, Klein-Flügge MC, Tankelevitch L, Papageorgiou GK, Aubry J, Sallet J, Rushworth MFS (2019) The macaque anterior cingulate cortex translates counterfactual choice value into actual behavioral change Nature Neuroscience 22,5: 797–808 (and bioRxiv 2018)

Verhagen L, Gallea C, Folloni D, Constans C, Jensen D, Ahnine H, Roumazeilles L, Santin M, Ahmed B, Lehericy S, Klein-Flügge MC, Krug K, Mars RB, Rushworth MFS, Pouget P, Aubry J, Sallet J (2019) Offline impact of transcranial focused ultrasound on cortical activation in primates. eLife 8: e40541 (and bioRxiv 2018)

Lockwood PL, Wittmann M, Apps MAJ, Klein-Flügge MC, Crockett MJ, Humphreys GW, Rushworth MFS (2018) Associative learning of self and other ownership, Nature Communications 9: 4747

Scholl J, Klein-Flügge MC (2018) Understanding psychiatric disease by capturing ecologically relevant features of learning and decision-making, Beh Brain Res 355:56-75

Klein-Flügge MC, Kennerley SW, Friston K, Bestmann S (2016) Neural signatures of value comparison in human cingulate cortex during decisions requiring an effort-reward trade-off. J. Neurosci. 36(39):10002-10015

Haemmerer D*, Bonaiuto J*, Klein-Flügge MC*, Bikson M, Bestmann S (2016), Selective alteration of human value decisions with medial frontal tDCS is predicted by changes in attractor dynamics [* These authors contributed equally to the work] Scientific Reports 6, Article number: 25160

Klein-Flügge MC, Kennerley SW, Saraiva AC, Penny WD, Bestmann S (2015) Behavioral Modeling of Human Choices Reveals Dissociable Effects of Physical Effort and Temporal Delay on Reward Devaluation, PLoS Comput Biol.11(3):e1004116

Klein-Flügge MC, Nobbs D, Pitcher JB, Bestmann S (2013) Variability of human cortico-spinal excitability tracks the state of action preparation, J. Neurosci. 33(13), 5564 –5572

Klein-Flügge MC*, Barron H*, Brodersen KH, Dolan RJ, Behrens TEJ (2013) Segregated encoding of reward-identity and stimulus-reward associations in human orbitofrontal cortex, J. Neurosci. 33(7), 3202–3211 [* These authors contributed equally to the work]

Nicolle A, Klein-Flügge MC, Hunt LT, Vlaev I, Dolan RJ, Behrens TEJ (2012) An agent independent axis for executed and modeled choice in medial prefrontal cortex, Neuron 75(6), 1114-21

Hall CN, Klein-Flügge MC, Howarth C, Attwell D (2012) Oxidative phosphorylation, not glycolysis, powers pre- and postsynaptic mechanisms underlying brain information processing, J. Neurosci. 32(26), 8940-51

Klein-Flügge MC, Bestmann S (2012) Time-dependent changes in human cortico-spinal excitability reveal value-based competition for action during decision processing, J. Neurosci. 32(24), 8373-82.

Klein-Flügge MC, Hunt LT, Bach DR, Dolan RJ, Behrens TEJ (2011) Dissociable Reward and Timing Signals in Human Midbrain and Ventral Striatum. Neuron 72(4), 654-664

Neubert F, Klein MC (2010). What is Driving Inhibition-Related Activity in the Frontal Lobe? J. Neurosci. 30(14), 4830–4832

Scholz J, Klein MC, BehrensTE, Johansen-Berg H (2009). Training induces changes in white-matter architecture, Nature Neuroscience, 12(11), 1370-1371 *** identified by Thomson Reuters as featured article: one of the most-cited papers from the last 2 years

Mars RB, Klein MC, Neubert F, Olivier E, Buch ER, Boorman ED, Rushworth MFS (2009). Short-Latency Influence of Medial Frontal Cortex on Primary Motor Cortex during Action Selection under Conflict. J. Neurosci., 29(21), 6926-6931.